In the past I have been something of a black and white purist in my print comics. It is so much cheaper to print, for one thing, and most of my very favorite comics are in black and white. I'm experimenting now with a comic that could be in color -- although I will probably still print it in b&w in addition to compare.
This is a story where color can add a sense of smell and temperature. I'm working on world building at the moment.